Chelsea Handler: 'This Means War' with Reese Witherspoon!

Chelsea Handler has been cast as Trish, the best friend to Reese Witherspoon‘s character in the upcoming flick This Means War.

Pic is about two CIA-agent best friends (Chris Pine and Tom Hardy) who wage an epic war for the affection of the same woman (Reese Witherspoon).

This isn’t the first major acting role for 35-year-old talk show host. Chelsea played the part of Mrs. Beck in the part live action, part animated comedy Hop, which will be released in theaters next April.

Chelsea, who was recently linked to 50 Cent, will begin shooting on This Means War later this month, according to Deadline.