Meet The Full Cast of CBS's New Medical Drama Series 'Good Sam'

The premiere of CBS’s new medical drama, Good Sam, is tonight!

The series will focus in Sophia Bush‘s Dr. Sam Griffith, a gifted heart surgeon who excels in her new leadership role as chief of surgery after her renowned boss falls into a coma.

However, when her former boss wakes up months later demanding to resume his duties, Sam is tasked with supervising this egotistical expert with a scalpel who never acknowledged her stellar talent.

Complicating matters, the caustic and arrogant Dr. Rob “Griff” Griffith also happens to be her father.

As Griff defies Sam’s authority and challenges her medical expertise, the big question becomes whether this father and daughter will ever be able to mend their own relationship as expertly as they heal the hearts of their patients.

Good Sam premieres TONIGHT, January 5 at 10 pm ET/PT on CBS.

Click inside to meet the full cast now!

Sophia Bush as Dr. Sam Griffith

Jason Isaacs as Dr. Rob “Griff” Griffith

Skye P. Marshall as Dr. Lex Trulie

Lex is described as an ambitious surgeon who shares a bond with Sam, as the only women in their department. That bond will be tested, though, when Sam replaces her father, to whom Lex is steadfastly loyal, as chief of surgery.

Michael Stahl-David as Dr. Caleb Tucker

Caleb is “a cocky resident with half the experience but twice the confidence of the other residents, all who outrank him.”

Omar Maskati as Dr. Isan M. Shah

Davi Santos as Dr. Joey Costa

Wendy Crewson as Vivian Katz

Edwin Hodge as Malcolm A. Kingsley

Malcolm’s family is the hospital’s wealthiest donor. But despite this, Malcolm works for a living as an administrative executive at the hospital, where he and Sam bond over the struggle to step out of their fathers’ shadows.