Christina Applegate Talks the Role She Passed on that Ultimately Went to Reese Witherspoon, 'Titanic' Rumors, Calling Out Candace Owens & More in 'Vanity Fair' Interview

Christina Applegate opened up in a revealing new interview.

The 51-year-old Dead to Me actress spoke to Vanity Fair about her future in acting after being diagnosed with MS. While she explained that she did plan to step back from in front of the camera, there was one role that was still in the works.

Looking back on her career, she highlighted a part that she passed on but came to regret saying no to. It ultimately went to Reese Witherspoon, and Christina explained why she said no in the first place. Speaking of casting, she addressed a big rumor that involved Titanic.

Christina also opened up about her decision to school Candace Owens after she complained about inclusivity in a SKIMS ad campaign.

Head inside to get the highlights from Christina Applegate’s interview…