Every 'Grey's Anatomy' Series Regular Actor Who Left the Show, From First to Most Recent

Grey’s Anatomy is one of the most popular TV shows of all time and it’s currently in the middle of season 19 on ABC.

Ellen Pompeo, the long-running star of the series, returned for the new season in a reduced role, signalling the end of her time on the show.

Throughout the last two decades, there have been 20 series regular actors who have left the series after spending many years at Grey Sloan Memorial Hospital.

Ellen is set to be the 21st series regular to leave when her time as a series regular is up in the new year.

Click through the slideshow to see all of the series regular actors who have left Grey’s Anatomy…