Patrick Dempsey is a Cross-dresser

McDreamy wears women’s clothes!

TV’s hottest doc Patrick Dempsey trades in his scrubs for a wedding dress while shooting scenes in downtown Manhattan on Sunday for his forthcoming 2008 flick Made of Honor.

The Paul Weiland-directed romantic comedy was on location in the Meatpacking District, where Patrick squeezed into a long pink satin wedding dress for the day’s filming.

10+ pictures inside of Dempsey cross-dressing…