Katherine Heigl Leaves Grey's Anatomy

Katherine Heigl and BFF costar T.R. Knight are hanging up their scrubs and leaving Grey’s Anatomy.

“Yes, she is [leaving],” co-star James Pickens Jr. (Dr. Richard Webber) tells Us Weekly. “Wherever Katherine goes, I wish her nothing but the best. [TR Knight's] going too. He just wanted to pursue other career paths.”

“Right now, the whole thing is in the hands of their agents and ABC’s lawyers,” an insider tells EW. “Something will probably be worked out soon, but it’s a safe bet that Katherine and T.R. won’t be returning as series regulars next season.”

WHAT DO YOU THINK of George and Izzie leaving the hit ABC medical drama — YAY or NAY?